June 21, 2010 – Caduet® (amlodipine besylate/atorvastatin calcium) was associated with a significantly reduced calculated 10-year risk of coronary heart disease (CHD) based on a Framingham risk assessment model. In addition, Caduet was shown to reduce calculated fatal cardiovascular disease (CVD) risk, as a secondary trial endpoint based on the SCORE risk assessment model. The Framingham and SCORE risk assessment models are widely used in the U.S. and EU, respectively. These data from the CRUCIAL (Cluster Randomized Usual Care vs. Caduet Investigation Assessing Long-term Risk) trial were presented yesterday at the 20th Scientific Meeting of the European Society of Hypertension (ESH) in Oslo, Norway.“The data presented at ESH are important because they show the potential benefit of Caduet, which combines blood pressure and cholesterol-lowering medications in a single pill, over usual care in a real-life clinical setting... Pfizer's Press Release -
